There are a lot of things that are involved here. Brett could be right that a smaller venturi would help. But maybe it is propped wrong or the fuel is wrong or line length (a little longer, a little leaner to start with).
If you are using high octane (high nitro) fuel, try going to a lower nitro content. You may be able to go to more prop (diameter) or less pitch. What muffler? If a tongue muffler, maybe a screw or two in the exhaust holes. And, yes, lower compression, will make it come on less strong, so a small head gasket increment could help.
With a Tower 40, these use .010 head gaskets. If you are using 5% nitro now, then changing out one .010 head gasked for an OS (.016) can help reduce the amount of "charge" in the loops.
But, yes, also check for upright and inverted. It could merely be the location of your tank, and you may need to raise that just slightly.
Give us specifics. If it is my engine, that is one thing. If it is Randy's or Lew's or someone elses, that is another. But each is set up differently. What prop are you using, muffler, fuel, line length, lap time? It is all important.